NACL Principal Investigators


Professor Robert D. O'Neill
Biosensors and Electrochemistry Laboratory

UCD School of Chemistry & Chemical Biology

Science Centre (South)

University College Dublin

Belfield, Dublin 4

Ireland.

Fax: +353-1-7162127

Tel: +353-1-7162314

E-mail:  Robert.ONeill@UCD.ie
Web:    Biosensors and Electrochemistry Laboratory

Outline CV: BSc (Chemistry, University College Dublin, 1976); Ryan Gold Medal (Chemistry, 1976); PhD (Electrochemistry,  supervised by Prof. David Feakins, UCD, 1980). Postdoctoral research (1980 – 83) with John Albery, FRS (Chemistry, Imperial College London) and Marianne Fillenz, MD, PhD (Physiology, Oxford University). Research Fellowships (1983 – 85) in Physiology (Worcester College, Oxford) and Neurochemistry (Beit Memorial Fellowship in Medical Research) at Oxford University. Appointed to UCD in 1985 and is now Professor of Electrochemistry. Currently, Science Foundation Ireland (SFI) Principal Investigator under the Investigator Programme, Basic Research, and Research Frontiers schemes.

Core Research Interests: Design and characterisation of amperometric sensors and biosensors; electrosynthesis of non-conducting polymer layers; kinetics of surface-bound enzymes; neurotransmitter glutamate and dopamine monitoring; brain vitamin-C/glutamate interactions.

Publications List.

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Professor John P. Lowry
Bioelectroanalysis Laboratory

Chemistry Department

National University of Ireland, Maynooth

Co. Kildare

Ireland.

Fax: +353-1-7083815

Tel: +353-1-7083770

E-mail: John.Lowry@NUIM.ie

Outline CV: BSc (Chemistry, University College Dublin, 1988); PhD (Bioelectrochemistry,  supervised by Prof. Robert D. O’Neill, UCD, 1992). Postdoctoral research (1992 – 94; 1997 – 98) with Prof. O’Neill, UCD. Marie Curie Fellow (1994 – 97) with Dr. Marianne Fillenz, MD, PhD (University Laboratory of Physiology, Oxford). Appointed as lecturer in Analytical Chemistry, Chemistry Department, National University of Ireland, Maynooth (NUIM) in 1998. Appointed as lecturer in Pharmacology, Pharmacology Department, Conway Institute of Biomolecular and Biomedical Research, UCD in 2004. Appointed to the Chair of Chemistry and Head of Department, NUIM in 2006.

Currently a Principal and Co-Investigator on grants awarded by: Science Foundation Ireland (SFI); the Health Research Board (HRB) Ireland; Enterprise Ireland; the Welcome Trust, UK; the Royal Society of Chemistry (RSC) and Engineering and Physical Sciences Research Council (EPSRC), UK; Eli Lilly and Company, Ltd., UK; and Solvay Pharmaceuticals, The Netherlands.

Core Research Interests: Application of brain microdialysis, and amperometric sensors and biosensors (e.g. glucose, lactate, tissue oxygen, blood-flow, glutamate, hydrogen peroxide, ascorbic acid and NO), in real-time studies of the interaction of various neurochemicals in the living brain. This work is targeted at understanding their role in various neurochemical processes (e.g. brain energy metabolism), and also in psychiatric (e.g. schizophrenia) and neurological (e.g. Parkinson’s disease) dysfunctions in order to develop treatments based on new drug discovery.

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Professor Jeffrey C. Glennon

NUIM & Solvay Pharmaceuticals

Outline CV: BSc (Physiology & Pharmacology, University College Dublin, 1996); Corrigan Medal (2001); PhD (Neuropharmacology, supervised by Dr. William O’Connor, UCD, 2000-2003). Predoctoral research (1993-1995) with Prof. Michael Rowan (Trinity College, Dublin) & Prof. Brian Lawlor (St. James Hospital, Dublin) in cognitive behavioural pharmacology and human electroencephalography. Appointed to Solvay Pharmaceuticals in 2000 as Groupleader mechanistic pharmacology and is now Director of In Vivo Neuropharmacology at Solvay Pharmaceuticals, the Netherlands and has recently been appointed Adjunct Professor of Pharmacology at the Department of Chemistry, National University of Ireland at Maynooth (NUIM). Currently, Lead Principal Investigator under the TI Pharma initiative within the Netherlands.

Core Research Interests: Models of psychiatric and neurological disorders, notably schizophrenia, bipolar disorder, addiction, Parkinson’s disease, epilepsy and Alzheimer’s disease. Focus on impulsivity and cognition. Mechanism of action underlying psychoactive drugs. Electrochemical signalling and energy metabolism dynamics in intact brain.

E-mail: Jeffrey.Glennon@NUIM.ie